Sequence editing by Apolipoprotein B RNA-editing catalytic component-B and epidemiological surveillance of transmitted HIV-1 drug resistance

DESIGN: Promiscuous guanine (G) to adenine (A) substitutions catalysed by apolipoprotein B RNA-editing catalytic component (APOBEC) enzymes are observed in a proportion of HIV-1 sequences in vivo and can introduce artifacts into some genetic analyses. The potential impact of undetected lethal editin...

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Autori principali: Gifford, Robert J., Rhee, Soo-Yon, Eriksson, Nicolas, Liu, Tommy F., Kiuchi, Mark, Das, Amar K., Shafer, Robert W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946849/
https://ncbi.nlm.nih.gov/pubmed/18356601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e3282f5e07a
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