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Combinations of oseltamivir and peramivir for the treatment of influenza A (H1N1) virus infections in cell culture and in mice

Oseltamivir and peramivir are being considered for combination treatment of serious influenza virus infections in humans. Both compounds are influenza virus neuraminidase inhibitors, and since peramivir binds tighter to the enzyme than oseltamivir carboxylate (the active form of oseltamivir), the po...

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Detalhes bibliográficos
Main Authors: Smee, Donald F., Hurst, Brett L., Wong, Min-Hui, Tarbet, E. Bart, Babu, Y.S., Klumpp, Klaus, Morrey, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946506/
https://ncbi.nlm.nih.gov/pubmed/20633577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2010.07.003
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