Attenuation of osteoarthritis progression by reduction of the discoidin domain receptor 2 in mice

OBJECTIVE: To investigate whether the reduction of discoidin domain receptor 2 (DDR2), a cell membrane tyrosine kinase receptor for native type II collagen, attenuates the progression of articular cartilage degeneration in mouse OA models. METHODS: Double-heterozygous mutant, type XI collagen- and D...

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Bibliographic Details
Main Authors: Xu, Lin, Servais, Jacqueline, Polur, Ilona, Kim, Doil, Lee, Peter L., Chung, Kimberly, Li, Yefu
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946478/
https://ncbi.nlm.nih.gov/pubmed/20518074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27582
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