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Replication of the Hepatitis B Virus Requires a Calcium-Dependent HBx-Induced G1 Phase Arrest of Hepatocytes
Chronic HBV infections cause hepatocellular carcinoma (HCC). Activities of the HBV HBx protein regulate HBV replication and may contribute to the development of HCC. We previously reported that HBx causes primary rat hepatocytes to exit G0 but stall in G1 phase of the cell cycle; entry into G1 stimu...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946470/ https://ncbi.nlm.nih.gov/pubmed/20719353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.07.042 |
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