Intraesophageal Manganese Superoxide Dismutase-Plasmid Liposomes Ameliorates Novel Total-Body and Thoracic Radiation Sensitivity of NOS1(−/−) Mice

The effect of deletion of the nitric oxide synthase 1 gene (NOS1(−/−)) on radiosensitivity was determined. In vitro, long-term cultures of bone marrow stromal cells derived from NOS1(−/−) were more radioresistant than cells from C57BL/6NHsd (wild-type), NOS2(−/−) or NOS3(−/−) mice. Mice from each st...

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Main Authors: Rajagopalan, Malolan S., Stone, Brandon, Rwigema, Jean-Claude, Salimi, Umar, Epperly, Michael W., Goff, Julie, Franicola, Darcy, Dixon, Tracy, Cao, Shaonan, Zhang, Xichen, Buchholz, Bettina M., Bauer, Anthony J., Choi, Serah, Bakkenist, Christopher, Wang, Hong, Greenberger, Joel S.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946247/
https://ncbi.nlm.nih.gov/pubmed/20726721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR2019.1
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