Long Term Administration of Endothelin Receptor Antagonist Improves Coronary Endothelial Function in Patients with Early Atherosclerosis

BACKGROUND: Endothelin (ET-1) is one of the most potent vasoconstrictors, and plays a seminal role in the pathogenesis of atherosclerosis. The current study was designed to test the hypothesis that long term treatment with an endothelin-A (ET(A)) receptor antagonist improves coronary endothelial fun...

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Main Authors: Reriani, Martin, Raichlin, Eugenia, Prasad, Abhiram, Mathew, Verghese, Pumper, Geralyn M., Nelson, Rebecca E., Lennon, Ryan, Rihal, Charanjit, Lerman, Lilach O., Lerman, Amir
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946239/
https://ncbi.nlm.nih.gov/pubmed/20733096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.110.967406
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