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Very High Affinity DNA Recognition by Bicyclic and Cross-Linked Oligonucleotides

We report the synthesis and DNA incorporation of a novel C-5 thiopropyne-substituted thymidine derivative which can be used to bring about covalent crosslinks between two noncomplementary DNA strands. This modified thymine pairs normally with adenine in duplex DNA and is shown not to be destabilizin...

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書誌詳細
主要な著者: Chaudhuri, Narayan C., Kool, Eric T.
フォーマット: Artigo
言語:Inglês
出版事項: 1995
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946160/
https://ncbi.nlm.nih.gov/pubmed/20882118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja00147a004
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