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Regulation of mitochondrial Ca(2+) and its effects on energetics and redox balance in normal and failing heart
Ca(2+) has been well accepted as a signal that coordinates changes in cytosolic workload with mitochondrial energy metabolism in cardiomyocytes. During increased work, Ca(2+) is accumulated in mitochondria and stimulates ATP production to match energy supply and demand. The kinetics of mitochondrial...
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Main Authors: | , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2009
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946065/ https://ncbi.nlm.nih.gov/pubmed/19390955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10863-009-9216-8 |
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