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Context dependent substitution biases vary within the human genome

BACKGROUND: Models of sequence evolution typically assume that different nucleotide positions evolve independently. This assumption is widely appreciated to be an over-simplification. The best known violations involve biases due to adjacent nucleotides. There have also been suggestions that biases e...

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Detalhes bibliográficos
Main Authors: Nevarez, P Andrew, DeBoever, Christopher M, Freeland, Benjamin J, Quitt, Marissa A, Bush, Eliot C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945941/
https://ncbi.nlm.nih.gov/pubmed/20843365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-462
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