Loading...

Highly Enantioselective Catalytic Dynamic Resolution of N-Boc-2-lithiopiperidine: Synthesis of (R)-(+)-N-Boc-Pipecolic Acid, (S)-(−)-Coniine, (S)-(+)-Pelletierine, (+)-β-Conhydrine, (S)-(−)-Ropivacaine, and Formal Synthesis of (−)-Lasubine II and (+)-Cermizine C

[Image: see text] The catalytic dynamic resolution (CDR) of rac-2-lithio-N-Boc-piperidine using chiral ligand 8 or its diastereomer 9, in the presence of TMEDA has led to the highly enantioselective syntheses of either enantiomer of 2-substituted piperidines using a wide range of electrophiles. The...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Beng, Timothy K., Gawley, Robert E.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945905/
https://ncbi.nlm.nih.gov/pubmed/20806976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja105772z
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!