Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis

The basic helix-loop-helix transcription factor stem cell leukemia gene (Scl) is a master regulator for hematopoiesis essential for hematopoietic specification and proper differentiation of the erythroid and megakaryocyte lineages. However, the critical downstream targets of Scl remain undefined. He...

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Hauptverfasser: Gekas, Christos, Rhodes, Katrin E., Gereige, Laurraine M., Helgadottir, Hildur, Ferrari, Roberto, Kurdistani, Siavash K., Montecino-Rodriguez, Encarnación, Bassel-Duby, Rhonda, Olson, Eric, Krivtsov, Andrei V., Armstrong, Scott, Orkin, Stuart H., Pellegrini, Matteo, Mikkola, Hanna K. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2009
Schlagworte:
Hematopoiesis and Stem Cells
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945827/
https://ncbi.nlm.nih.gov/pubmed/19211936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-167577
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