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Functional differences in the cytochrome P450 1 family enzymes from Zebrafish (Danio rerio) using heterologously expressed proteins

Mammalian cytochrome P4501 (CYP1) genes are well characterized, but in other vertebrates only the functions of CYP1A genes have been well studied. We determined the catalytic activity of zebrafish CYP1A, CYP1B1, CYP1C1, CYP1C2 and CYP1D1 proteins using 11 fluorometric substrates and benzo[a]pyrene (...

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書誌詳細
主要な著者: Scornaienchi, Marcus L., Thornton, Cammi, Willett, Kristine L., Wilson, Joanna Y.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945726/
https://ncbi.nlm.nih.gov/pubmed/20599672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.06.018
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