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Med24 and Mdh2 are required for Drosophila larval salivary gland cell death

The steroid hormone ecdysone triggers the rapid destruction of larval tissues through transcriptional cascades that culminate in rpr and hid expression and caspase activation. Here we show that mutations in Mdh2 and Med24 block caspase cleavage and larval salivary gland cell death. Mdh2 encodes a pr...

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Autors principals: Wang, Lei, Lam, Geanette, Thummel, Carl S.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945606/
https://ncbi.nlm.nih.gov/pubmed/20063412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22213
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