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Single Site Mutations in the Hetero-oligomeric Mrp Antiporter from Alkaliphilic Bacillus pseudofirmus OF4 That Affect Na(+)/H(+) Antiport Activity, Sodium Exclusion, Individual Mrp Protein Levels, or Mrp Complex Formation
Mrp systems are widely distributed and structurally complex cation/proton antiporters. Antiport activity requires hetero-oligomeric complexes of all six or seven hydrophobic Mrp proteins (MrpA–MrpG). Here, a panel of site-directed mutants in conserved or proposed motif residues was made in the Mrp N...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2945585/ https://ncbi.nlm.nih.gov/pubmed/20624916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.118661 |
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