ALTERED MICROGLIAL COPPER HOMEOSTASIS IN A MOUSE MODEL OF ALZHEIMER’S DISEASE

Alzheimer’s disease (AD) is characterized by progressive neurodegeneration associated with the aggregation and deposition of β-amyloid (Aβ(40) and Aβ(42)) peptide in senile plaques. Recent studies suggest that copper may play an important role in AD pathology. Copper concentrations are elevated in a...

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Detalhes bibliográficos
Main Authors: Zheng, Zhiqiang, White, Carine, Lee, Jaekwon, Peterson, Troy S., Bush, Ashley I., Sun, Grace, Weisman, Gary A., Petris, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945454/
https://ncbi.nlm.nih.gov/pubmed/20626553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06888.x
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