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The frequency-dependence of the nicotine-induced inhibition of dopamine is controlled by the α7 nicotinic receptor

Voltammetric analyses show that low (100–500 nM) doses of nicotine regulate striatal dopamine by inhibiting release evoked by a single stimulation to a greater extent than release evoked by high frequency stimulations. This frequency-dependent inhibition is because of nicotine desensitizing heterome...

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Detalhes bibliográficos
Main Authors: Seipel, Andrew T., Yakel, Jerrel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945408/
https://ncbi.nlm.nih.gov/pubmed/20598018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06883.x
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