Deficiency in the Serum-Derived Hyaluronan-Associated Protein-Hyaluronan Complex Enhances Airway Hyperresponsiveness in a Murine Model of Asthma

BACKGROUND: Serum-derived hyaluronan (HA)-associated proteins (SHAPs), the heavy chains of inter-α-trypsin inhibitor, covalently bind to HA to form the SHAP-HA complex. The SHAP-HA complex is involved in the pathophysiology of inflammatory diseases, including rheumatoid arthritis. We investigated wh...

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Detalhes bibliográficos
Main Authors: Zhu, Long, Zhuo, Lisheng, Kimata, Koji, Yamaguchi, Etsuro, Watanabe, Hideto, Aronica, Mark A., Hascall, Vincent C., Baba, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945275/
https://ncbi.nlm.nih.gov/pubmed/20484920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000314362
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