Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis

INTRODUCTION: Antifibrinolytic agents are commonly used during cardiac surgery to minimize bleeding. Because of safety concerns, aprotinin was withdrawn from the market in 2007. Since then, tranexamic acid (TXA) has become the antifibrinolytic treatment of choice in many heart centers. The safety pr...

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Detalhes bibliográficos
Main Authors: Sander, Michael, Spies, Claudia D, Martiny, Viktoria, Rosenthal, Christoph, Wernecke, Klaus-Dieter, von Heymann, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945131/
https://ncbi.nlm.nih.gov/pubmed/20682059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc9216
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