High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1β in osteoarthritic synoviocytes

INTRODUCTION: High mobility group box 1 (HMGB1) is released by necrotic cells or secreted in response to inflammatory stimuli. Extracellular HMGB1 may act as a pro-inflammatory cytokine in rheumatoid arthritis. We have recently reported that HMGB1 is released by osteoarthritic synoviocytes after act...

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Autori principali: García-Arnandis, Isabel, Guillén, Maria Isabel, Gomar, Francisco, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Alcaraz, Maria José
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945068/
https://ncbi.nlm.nih.gov/pubmed/20799933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3124
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