Decreased detoxification genes and genome size make the human body louse an efficient model to study xenobiotic metabolism

The human body louse, Pediculus humanus humanus, has one of the smallest insect genomes, containing ~10,775 annotated genes (Kirkness et al. 2010). Annotation of detoxification [cytochrome P450 monooxygenase (P450), glutathione-S-transferase (GST), esterase (Est), and ATP-binding cassette transporte...

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Main Authors: Lee, Si Hyeock, Kang, Jae Soon, Min, Jee Sun, Yoon, Kyong Sup, Strycharz, Joseph P., Johnson, Reed, Mittapalli, Omprakash, Margam, Venu M., Sun, Weilin, Li, Hong-Mei, Xie, Jun, Wu, Jing, Kirkness, Ewen F., Berenbaum, May R., Pittendrigh, Barry R., Clark, J. Marshall
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944910/
https://ncbi.nlm.nih.gov/pubmed/20561088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2583.2010.01024.x
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