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Molecular Cloning and Characterization of the Human ErbB4 Gene: Identification of Novel Splice Isoforms in the Developing and Adult Brain

ErbB4 is a growth factor receptor tyrosine kinase essential for neurodevelopment. Genetic variation in ErbB4 is associated with schizophrenia and risk-associated polymorphisms predict overexpression of ErbB4 CYT-1 isoforms in the brain in the disorder. The molecular mechanism of association is uncle...

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Detalhes bibliográficos
Main Authors: Tan, Wei, Dean, Michael, Law, Amanda J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944867/
https://ncbi.nlm.nih.gov/pubmed/20886074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012924
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