Opto-Current-Clamp Actuation of Cortical Neurons Using a Strategically Designed Channelrhodopsin

BACKGROUND: Optogenetic manipulation of a neuronal network enables one to reveal how high-order functions emerge in the central nervous system. One of the Chlamydomonas rhodopsins, channelrhodopsin-1 (ChR1), has several advantages over channelrhodopsin-2 (ChR2) in terms of the photocurrent kinetics....

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Autors principals: Wen, Lei, Wang, Hongxia, Tanimoto, Saki, Egawa, Ryo, Matsuzaka, Yoshiya, Mushiake, Hajime, Ishizuka, Toru, Yawo, Hiromu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944835/
https://ncbi.nlm.nih.gov/pubmed/20886118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012893
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