Oral methylphenidate normalizes cingulate activity in cocaine addiction during a salient cognitive task

Anterior cingulate cortex (ACC) hypoactivations during cognitive demand are a hallmark deficit in drug addiction. Methylphenidate (MPH) normalizes cortical function, enhancing task salience and improving associated cognitive abilities, in other frontal lobe pathologies; however, in clinical trials,...

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Bibliografiske detaljer
Main Authors: Goldstein, Rita Z., Woicik, Patricia A., Maloney, Thomas, Tomasi, Dardo, Alia-Klein, Nelly, Shan, Juntian, Honorio, Jean, Samaras, Dimitris, Wang, Ruiliang, Telang, Frank, Wang, Gene-Jack, Volkow, Nora D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944718/
https://ncbi.nlm.nih.gov/pubmed/20823246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011455107
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