Membrane Efflux and Influx Modulate both Multidrug Resistance and Virulence of Klebsiella pneumoniae in a Caenorhabditis elegans Model

Cross-resistance to cefoxitin (FOX), chloramphenicol (CMP), and quinolones (nalidixic acid [NAL]) related to a putative efflux system overexpression has recently been reported for Klebsiella pneumoniae. The potential impact of this multidrug resistance (MDR) on the virulence of K. pneumoniae was eva...

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Autores principales: Bialek, Suzanne, Lavigne, Jean-Philippe, Chevalier, Jacqueline, Marcon, Estelle, Leflon-Guibout, Véronique, Davin, Anne, Moreau, Richard, Pagès, Jean-Marie, Nicolas-Chanoine, Marie-Hélène
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944602/
https://ncbi.nlm.nih.gov/pubmed/20679507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01607-09
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