Akt pathway is hypoactivated by synergistic actions of diabetes mellitus and hypercholesterolemia resulting in advanced coronary artery disease

Atherosclerosis is an inflammatory process leading to enhanced cellular proliferation, apoptosis, and vasa vasorum (VV) neovascularization. While both diabetes mellitus (DM) and hypercholesterolemia (HC) predispose to atherosclerosis, the precise interaction of these risk factors is unclear. Akt is...

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Autores principales: Hamamdzic, Damir, Fenning, Robert S., Patel, Dhavalkumar, Mohler, Emile R., Orlova, Ksenia A., Wright, Alexander C., Llano, Raul, Keane, Martin G., Shannon, Richard P., Birnbaum, Morris J., Wilensky, Robert L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2010
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944488/
https://ncbi.nlm.nih.gov/pubmed/20601459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00071.2010
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