Intranasal Delivery of an IgA Monoclonal Antibody Effective against Sublethal H5N1 Influenza Virus Infection in Mice

Highly pathogenic avian H5N1 influenza viruses are endemic in poultry in Asia and pose a pandemic threat to humans. Since the deployment of vaccines against a pandemic strain may take several months, adequate antiviral alternatives are needed to minimize the effects and the spread of the disease. Pa...

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Bibliographische Detailangaben
Hauptverfasser: Ye, Jianqiang, Shao, Hongxia, Hickman, Danielle, Angel, Matthew, Xu, Kemin, Cai, Yibin, Song, Haichen, Fouchier, Ron A. M., Qin, Aijian, Perez, Daniel R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Microbial Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944460/
https://ncbi.nlm.nih.gov/pubmed/20668143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00002-10
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