Mitogen-activated protein kinase and its activator are regulated by hypertonic stress in Madin-Darby canine kidney cells.

Madin-Darby canine kidney cells behave like the renal medulla and accumulate small organic solutes (osmolytes) in a hypertonic environment. The accumulation of osmolytes is primarily dependent on changes in gene expression of enzymes that synthesize osmolytes (sorbitol) or transporters that uptake t...

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Pubblicato in:	J Clin Invest
Autori principali:	Itoh, T, Yamauchi, A, Miyai, A, Yokoyama, K, Kamada, T, Ueda, N, Fujiwara, Y
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294445/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8200972/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117245
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