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Three Doses of an Experimental Detoxified L3-Derived Lipooligosaccharide Meningococcal Vaccine Offer Good Safety but Low Immunogenicity in Healthy Young Adults

This open, randomized phase I study evaluated the safety and reactogenicity of an experimental meningococcal serogroup B (MenB) vaccine obtained from outer membrane vesicle detoxified L3-derived lipooligosaccharide. Healthy young adults (n = 150) were randomized to receive either experimental vaccin...

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Autors principals: Bonvehí, Pablo, Boutriau, Dominique, Casellas, Javier, Weynants, Vincent, Feron, Christiane, Poolman, Jan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944444/
https://ncbi.nlm.nih.gov/pubmed/20660140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00129-10
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