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Antisense proliferating cell nuclear antigen oligonucleotides inhibit intimal hyperplasia in a rat carotid artery injury model.

We have used antisense phosphorothioate oligonucleotides to define the role played by proliferating cell nuclear antigen (PCNA) in neointimal accumulation of smooth muscle cells in a rat carotid artery injury model. The short-term extraluminal delivery of 250 nmol of antisense oligonucleotides, but...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Simons, M, Edelman, E R, Rosenberg, R D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294440/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7911126/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117240
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