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Progressive renal papillary calcification and ureteral stone formation in mice deficient for Tamm-Horsfall protein

Mammalian urine contains a range of macromolecule proteins that play critical roles in renal stone formation, among which Tamm-Horsfall protein (THP) is by far the most abundant. While THP is a potent inhibitor of crystal aggregation in vitro and its ablation in vivo predisposes one of the two exist...

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Hlavní autoři: Liu, Yan, Mo, Lan, Goldfarb, David S., Evan, Andrew P., Liang, Fengxia, Khan, Saeed R., Lieske, John C., Wu, Xue-Ru
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944300/
https://ncbi.nlm.nih.gov/pubmed/20591941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00243.2010
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