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Regulation of podocyte BK(Ca) channels by synaptopodin, Rho, and actin microfilaments

Mechanosensitive large-conductance Ca(2+)-activated K(+) channels encoded by the Slo1 gene (BK(Ca) channels) are expressed in podocytes. Here we show that BK(Ca) channels reciprocally coimmunoprecipitate with synaptopodin (Synpo) in mouse glomeruli, in mouse podocytes, and in a heterologous expressi...

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Autors principals: Kim, Eun Young, Suh, Jae Mi, Chiu, Yu-Hsin, Dryer, Stuart E.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944294/
https://ncbi.nlm.nih.gov/pubmed/20630939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00206.2010
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