Synergism in hyperhomocysteinemia and diabetes: role of PPAR gamma and tempol

BACKGROUND: Hyperhomocysteinemia (HHcy) and hyperglycemia cause diabetic cardiomyopathy by inducing oxidative stress and attenuating peroxisome proliferator- activated receptor (PPAR) gamma. However, their synergistic contribution is not clear. METHODS: Diabetic Akita (Ins2+/-) and hyperhomocysteine...

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Detalhes bibliográficos
Main Authors: Mishra, Paras K, Tyagi, Neetu, Sen, Utpal, Joshua, Irving G, Tyagi, Suresh C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944245/
https://ncbi.nlm.nih.gov/pubmed/20828387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-9-49
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