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Design and Synthesis of Substrates for Newborn Screening of Maroteaux-Lamy and Morquio A Syndromes
In continued efforts to develop enzymatic assays for lysosomal storage diseases appropriate for newborn screening laboratories we have synthesized novel and specific enzyme substrates for Maroteaux-Lamy (MPS VI) and Morquio A (MPS IVA) diseases. The sulfated monosaccharide derivatives were found to...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944228/ https://ncbi.nlm.nih.gov/pubmed/20833037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.08.080 |
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