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A six-generation Chinese family in haplogroup B4C1C exhibits high penetrance of 1555A > G-induced hearing Loss

BACKGROUND: The 1555A > G mutation is the most common cause of aminoglycoside-induced and non-syndromic deafness. However, the variable clinical phenotype and incomplete penetrance of A1555G-induced hearing loss complicate our understanding of this mutation. Environmental factors, nuclear genes,...

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Detalhes bibliográficos
Main Authors: Bai, Yan, Wang, Zhengmin, Dai, Wenjia, Li, Qingzhong, Chen, Guoling, Cong, Ning, Guan, Minxin, Li, Huawei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944124/
https://ncbi.nlm.nih.gov/pubmed/20822538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-129
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