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Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4
The chromatin remodelling factor chromodomain helicase DNA-binding protein 4 (CHD4) is a catalytic subunit of the NuRD transcriptional repressor complex. Here, we reveal novel functions for CHD4 in the DNA-damage response (DDR) and cell-cycle control. We show that CHD4 mediates rapid poly(ADP-ribose...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944064/ https://ncbi.nlm.nih.gov/pubmed/20693977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.188 |
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