Changes in expression of NMDA-NR1 receptor subunits in the rostral ventromedial medulla modulates pain behaviors

Increasing the NR1 subunit of the NMDA receptor in the RVM produces hyperalgesia, while decreasing NR1 in the RVM produces hypoalgesia and prevents development of chronic muscle hyperalgesia.

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Bibliographic Details
Main Authors: Da Silva, Luis Felipe S., Walder, Roxanne Y., Davidson, Beverly L., Wilson, Steven P., Sluka, Kathleen A.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943935/
https://ncbi.nlm.nih.gov/pubmed/20688433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2010.06.037
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