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Green Tea Catechin, Epigallocatechin Gallate, Suppresses Signaling by the dsRNA Innate Immune Receptor RIG-I

BACKGROUND: The Innate immune system constitutes the first line of defense against pathogen infections. The Retinoic acid-inducible gene I (RIG-I) receptor recognizes triphosphorylated ssRNAs and dsRNA to initiate downstream signaling of interferon response. However, unregulated activity of these re...

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Detaylı Bibliyografya
Asıl Yazarlar: Ranjith-Kumar, C. T., Lai, Yvonne, Sarisky, Robert T., Cheng Kao, C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943919/
https://ncbi.nlm.nih.gov/pubmed/20877565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012878
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