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Reference-Free Validation of Short Read Data

BACKGROUND: High-throughput DNA sequencing techniques offer the ability to rapidly and cheaply sequence material such as whole genomes. However, the short-read data produced by these techniques can be biased or compromised at several stages in the sequencing process; the sources and properties of so...

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Autores principales: Schröder, Jan, Bailey, James, Conway, Thomas, Zobel, Justin
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943903/
https://ncbi.nlm.nih.gov/pubmed/20877643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012681
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