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Triglyceride Blisters in Lipid Bilayers: Implications for Lipid Droplet Biogenesis and the Mobile Lipid Signal in Cancer Cell Membranes

Triglycerides have a limited solubility, around 3%, in phosphatidylcholine lipid bilayers. Using millisecond-scale course grained molecular dynamics simulations, we show that the model lipid bilayer can accommodate a higher concentration of triolein (TO) than earlier anticipated, by sequestering tri...

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Main Authors: Khandelia, Himanshu, Duelund, Lars, Pakkanen, Kirsi I., Ipsen, John H.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943900/
https://ncbi.nlm.nih.gov/pubmed/20877640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012811
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