Prostacyclin synthesis in ovine pulmonary artery is developmentally regulated by changes in cyclooxygenase-1 gene expression.

Prostacyclin (PGI2) is a key mediator of pulmonary vasomotor tone during late gestation and in the newborn, and its production in whole lung increases during that period. We investigated the developmental regulation of PGI2 synthesis in ovine intrapulmonary artery (PA) segments from 110 to 115 d (F1...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Brannon, T S, North, A J, Wells, L B, Shaul, P W
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294372/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8182155/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117220
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