Downregulation of adenylylcyclase types V and VI mRNA levels in pacing-induced heart failure in dogs.

We have shown that the heart expresses two distinct forms of adenylylcyclase mRNA, types V and VI. In this study we have characterized the expression of these two mRNA species in heart failure generated by overdrive pacing at a rate of 240 beats/min. After 4 wk, left ventricular end-diastolic pressu...

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Pubblicato in:	J Clin Invest
Autori principali:	Ishikawa, Y, Sorota, S, Kiuchi, K, Shannon, R P, Komamura, K, Katsushika, S, Vatner, D E, Vatner, S F, Homcy, C J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294370/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8182154/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117219
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