tRNA(Sec) is transcribed by RNA polymerase II in Trypanosoma brucei but not in humans

Nuclear-encoded tRNAs are universally transcribed by RNA polymerase III (Pol-III) and contain intragenic promoters. Transcription of vertebrate tRNA(Sec) however requires extragenic promoters similar to Pol-III transcribed U6 snRNA. Here, we present a comparative analysis of tRNA(Sec) transcription...

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Detalhes bibliográficos
Main Authors: Aeby, Eric, Ullu, Elisabetta, Yepiskoposyan, Hasmik, Schimanski, Bernd, Roditi, Isabel, Mühlemann, Oliver, Schneider, André
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943599/
https://ncbi.nlm.nih.gov/pubmed/20444878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq345
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