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A two-parameter generalized Poisson model to improve the analysis of RNA-seq data

Deep sequencing of RNAs (RNA-seq) has been a useful tool to characterize and quantify transcriptomes. However, there are significant challenges in the analysis of RNA-seq data, such as how to separate signals from sequencing bias and how to perform reasonable normalization. Here, we focus on a funda...

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Hlavní autoři: Srivastava, Sudeep, Chen, Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943596/
https://ncbi.nlm.nih.gov/pubmed/20671027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq670
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