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Identification of β-catenin binding regions in colon cancer cells using ChIP-Seq
Deregulation of the Wnt/β-catenin signaling pathway is a hallmark of colon cancer. Mutations in the adenomatous polyposis coli (APC) gene occur in the vast majority of colorectal cancers and are an initiating event in cellular transformation. Cells harboring mutant APC contain elevated levels of the...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943592/ https://ncbi.nlm.nih.gov/pubmed/20460455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq363 |
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