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Homeodomain only protein is required for the function of induced regulatory T cells in dendritic cell-mediated peripheral T cell unresponsiveness

Induced T regulatory (iT(reg)) cells can be generated by peripheral dendritic cells (DCs) that mediate T cell-unresponsiveness to re-challenge with antigen. The molecular factors required for the function of such iT(reg) cells remain unknown. We report a critical role for the transcription co-factor...

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Autors principals: Hawiger, Daniel, Wan, Yisong Y., Eynon, Elizabeth E., Flavell, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943559/
https://ncbi.nlm.nih.gov/pubmed/20802482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1929
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