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Activation of brain endothelium by Pneumococcal neuraminidase NanA promotes bacterial internalization

Streptococcus pneumoniae (SPN), the leading cause of meningitis in children and adults worldwide, is associated with an overwhelming host inflammatory response and subsequent brain injury. Here we examine the global response of the blood-brain barrier to SPN infection and the role of neuraminidase A...

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Autors principals: Banerjee, Anirban, van Sorge, Nina M., Sheen, Tamsin R., Uchiyama, Satoshi, Mitchell, Tim J., Doran, Kelly S.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943548/
https://ncbi.nlm.nih.gov/pubmed/20557315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2010.01490.x
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