Hepatitis C Virus Core Protein Induces Neuroimmune Activation and Potentiates Human Immunodeficiency Virus-1 Neurotoxicity

BACKGROUND: Hepatitis C virus (HCV) genomes and proteins are present in human brain tissues although the impact of HIV/HCV co-infection on neuropathogenesis remains unclear. Herein, we investigate HCV infectivity and effects on neuronal survival and neuroinflammation in conjunction with HIV infectio...

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Main Authors: Vivithanaporn, Pornpun, Maingat, Ferdinand, Lin, Liang-Tzung, Na, Hong, Richardson, Christopher D., Agrawal, Babita, Cohen, Éric A., Jhamandas, Jack H., Power, Christopher
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943470/
https://ncbi.nlm.nih.gov/pubmed/20877724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012856
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