A Key Commitment Step in Erythropoiesis Is Synchronized with the Cell Cycle Clock through Mutual Inhibition between PU.1 and S-Phase Progression

Hematopoietic progenitors undergo differentiation while navigating several cell division cycles, but it is unknown whether these two processes are coupled. We addressed this question by studying erythropoiesis in mouse fetal liver in vivo. We found that the initial upregulation of cell surface CD71...

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Detalhes bibliográficos
Main Authors: Pop, Ramona, Shearstone, Jeffrey R., Shen, Qichang, Liu, Ying, Hallstrom, Kelly, Koulnis, Miroslav, Gribnau, Joost, Socolovsky, Merav
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943437/
https://ncbi.nlm.nih.gov/pubmed/20877475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000484
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