Loss of Cartilage Structure, Stiffness, and Frictional Properties in Mice Lacking PRG4

OBJECTIVE: To assess the role of the glycoprotein PRG4 in joint lubrication and chondroprotection by measuring friction, stiffness, surface topography, and subsurface histology of the hip joints of Prg4(−/−) and wild-type (WT) mice. METHODS: Friction and elastic modulus were measured in cartilage fr...

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Detaylı Bibliyografya
Asıl Yazarlar: Coles, Jeffrey M, Zhang, Ling, Blum, Jason J, Warman, Matthew L, Jay, Gregory D, Guilak, Farshid, Zauscher, Stefan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley Subscription Services, Inc., A Wiley Company 2010
Konular:
Cartilage Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943386/
https://ncbi.nlm.nih.gov/pubmed/20191580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27436
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