μ-Opioid Receptor Endocytosis Prevents Adaptations in Ventral Tegmental Area GABA Transmission Induced during Naloxone-Precipitated Morphine Withdrawal

Chronic morphine drives adaptations in synaptic transmission thought to underlie opiate dependence. Here we examine the role of μ-opioid receptor (MOR) trafficking in one of these adaptations, specifically, changes in GABA transmission in the ventral tegmental area (VTA). To address this question, w...

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Main Authors: Madhavan, Anuradha, He, Li, Stuber, Garret D., Bonci, Antonello, Whistler, Jennifer L.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2010
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943338/
https://ncbi.nlm.nih.gov/pubmed/20203187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4634-09.2010
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